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Developed as part of a group of drugs called GLP-1 receptor agonists, semaglutide works in specific ways in the body to help people control their blood sugar levels, manage their weight, and even reduce certain risks associated with type 2 diabetes, such as heart disease

On 24 November 2025, Novo Nordisk reported that oral semaglutide had failed to slow Alzheimers disease in the EVOKE and EVOKE+ trials, which together enrolled 3,808 participants and stand as the largest evaluation of this drug class in any neurodegenerative condition [1]